Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health.

Launched by EUNICE DUBE · Jan 20, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how to manage Hepatitis B (Hep B) and Human Papilloma Virus (HPV) related cancers in women and high school students. The main goal is to see how common these infections are among women aged 13 to 45 who visit certain clinics, and to understand the behaviors of high school students that might put them at risk for developing cancers of the cervix and liver. Researchers want to find out if screening for cancer and providing vaccines for Hep B and HPV, along with mental health support, can help prevent these cancers in these groups.

To participate in this study, women and young females must be between 13 and 45 years old and seeking health services, while high school students must be at least 13 years old and enrolled in specific schools. Participants should not have received the Hep B and HPV vaccines before and should be able to understand and respond to some simple questions about their health. If eligible, participants can expect to answer questions about their health and behaviors, and they will have the opportunity to receive vaccinations if they haven’t had them yet. This trial is not currently recruiting participants, but it aims to provide important information about preventing cancer in these communities.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * For the High school students' group:
• • All students aged 13 years and older, enrolled at the selected Mtshabezi and Matopo High Schools in the Gwanda and Matobo Rural Districts during the five-year period of the project are eligible to participate in the study.
• • Ability to understand and respond to questions on the Youth Risk Behavior Scree questionnaire and PHQ-9 scale.
• • Relevant history of HPV vaccine administration. Ability to obtain parental/guardian consent for participation.
• • - For the women group: All women and young female adults thirteen to forty-five years old and requesting health services for prenatal, post-partum, family planning and other care during the five-year project period are eligible to participate.
• • Must not have received Hep B and HPV vaccine in the past and have no known contraindications to either of these two vaccines.
• • Are able to understand and respond to the PHQ-9 and Edinburgh Postnatal Depression scales.
• • Must have a valid consent for participation in the study.
• Exclusion Criteria:
• • males who are not enrolled in these participating High Schools.
• • children below the age of thirteen who are not enrolled in high schools and are not seeking prenatal, post-partum and family planning services at these selected health facilities during the project period.
• • Any eligible potential participant without a valid consent.
• • Any potential participant who is excluded by a doctor or midwife for a known contraindicating medical condition that can lead to potential harm to the participant or staff.
• • Any potential participant who is unable to understand and respond to the questions being asked.
• • Participants with proof of prior vaccination will be excluded from this part of the study.