Type 1 Diabetes Autonomic and Vascular Function

Launched by UNIVERSITY OF TEXAS AT AUSTIN · Jan 15, 2025

Keywords

ClinConnect Summary

This is a prospective observational study that looks at how the body’s automatic control systems (like heart rate and blood pressure) and blood flow in the blood vessels work in people with Type 1 diabetes compared to healthy adults. Researchers will measure vascular function (blood flow in the arms) and autonomic function (how the body regulates blood pressure) during rest and during light handgrip exercise. The study will compare two groups: adults with Type 1 diabetes and healthy controls matched for age, sex, and weight.

If you’re eligible, you’d be in one of two groups: Type 1 diabetes or healthy control. Key eligibility includes ages 18 to 70 and a BMI below 40. About 72 people are planned to participate. Participants will have tests at the University of Texas at Austin, including blood tests (glucose, cholesterol, oxidative stress, and inflammatory markers) and noninvasive measurements of blood flow and blood pressure during controlled handgrip tasks. The study is ongoing with no results yet, and it is designed to help us understand whether Type 1 diabetes affects autonomic and vascular function in adults.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Type 1 diabetes or a Healthy control
• Exclusion Criteria:
• • BMI \> 40kg/m2
• • Cancer with current treatment
• • HIV
• • Smoker cigarettes
• • Are pregnant or breastfeeding