Fibromyalgia and Sleep Disorder Treatment

Launched by UPPSALA UNIVERSITY · Jan 15, 2025

Keywords

ClinConnect Summary

The main aim of this study is to evaluate the interaction between pain and sleep, both directly by comparing outcome measures of pain and sleep, and out of one inflammatory perspective using proteomics analyzes. Currently, there is a need for studies that highlight both the above-mentioned interaction and how the inflammatory response in the central nervous system as well as in the systemic circulation is involved. The cohort in existing study (FINE study) is already being used to find associations between these, but as it is a cross-sectional study, the design cannot determinate the causal...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Fibromyalgia according to 1990 and 2016 ACR (American College of Rheumatology criteria)
• • Included in FINE study
• • Sleep disorder
• Exclusion Criteria:
• • Other autoimmune or neuroinflammatory diseases than FM.
• • Other dominating pain conditions other than FM (e.g., severe pain due to osteoarthritis, disc herniations etc).
• • Severe somatic or psychiatric diseases that would preclude participation or influence results (e.g., cancer, infectious diseases etc).
• • Pregnancy.
• • Inability to speak and understand Swedish.
• • Treatment with anticoagulants.
• • High intracranial pressure.
• • Ongoing infections.
• • Hemophilia.