Construction and Validation of a Prediction Model for All - Cause Mortality Within 30 Days After Surgery in Critically Ill Patients Undergoing Emergency Gastrointestinal Surgery

Launched by QUAN WANG · Jan 16, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on creating and testing a new model to predict the risk of death within 30 days after emergency gastrointestinal surgery. These surgeries are important for treating serious digestive issues but can lead to complications like infections, which can be very dangerous. Current methods for predicting the risk of death after such surgeries are not very effective, especially for critically ill patients. By developing a better prediction model, the researchers hope to help doctors identify high-risk patients early on so they can provide more targeted care.

To participate in this trial, individuals need to be over 18 years old and have undergone emergency gastrointestinal surgery while meeting certain critical health conditions afterward, such as needing help with breathing or having severe heart issues. The study will collect and analyze data from patients in two phases: first, looking back at past surgeries, and then following new patients for a short period after their surgery. This research aims to improve patient outcomes and reduce complications, ultimately enhancing recovery after surgery. Participants will be closely monitored, and their health information will be used to help build a reliable tool for doctors.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \> 18 years old; Underwent emergency gastrointestinal surgery \[referring to the tenth edition of the International Classification of Diseases (ICD - 10)\]; Met any of the following criteria for critically ill patients after surgery: those who still required ventilator - assisted ventilation after the surgery; those who needed norepinephrine infusion at a dose \> 1.0 μg/kg/min and even required combination with other vasopressor drugs to maintain blood pressure; those with severe arrhythmia; those with combined failure of other organ functions.
• Exclusion Criteria:
• • The surgical site is superficial and does not involve the abdominal cavity. Cases with data missing by more than 30%. Patients who died during the operation, or those for whom treatment was terminated or abandoned.
• • Cases complicated with multiple injuries. Patients participating in other clinical studies.