Exploration of Repeated High-frequency Transcranial Magnetic Stimulation for the Treatment of Acute Phase Aphasia in Post-stroke Patients
Launched by FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY · Jan 16, 2025
Trial Information
Current as of August 20, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Post stroke aphasia (PSA) is an acquired communication disorder caused by brain injury, characterized by various functional impairments such as self speech, repetition, naming, auditory comprehension, reading, and writing. PSA is one of the serious sequelae of stroke, which seriously affects the quality of life of patients. Early intervention in speech therapy can to some extent restore patients' functional communication abilities. Transcranial magnetic stimulation (TMS) is currently the most widely used non-invasive therapy. TMS can generate a magnetic field through the principle of magnet...
Gender
ALL
Eligibility criteria
- • Inclusion Criteria:1) Age ≥ 18 years old 2) Head MR confirms new onset of cerebral infarction, and aphasia symptoms are caused by cerebral infarction 3) Patient's hospitalization history is within 7 days 4) Can cooperate to complete all required inspection items and scales 5) Sign informed consent form 6) Right handed -
- • Exclusion Criteria:1)Patients with aphasia caused by non cerebral infarction,2) Non acute phase cerebral infarction patients with a course of more than 7 days 3) Severe neurological disorders other than stroke, such as epilepsy and hemorrhagic stroke, are combined 4) Patients with poor general condition and unable to complete relevant examinations and scale scores, such as patients with malignant arrhythmia, tumor, severe infection, malignant hypertension, diabetes hyperosmolar coma, etc 5) Previous or current comorbidities of severe mental illnesses, such as depression, schizophrenia, etc 6) Patients who have previously or currently taken sedatives or large amounts of sleep aids 7) Contraindications for combined transcranial magnetic stimulation: presence of metal or other implants (such as pacemakers) in the body 8) Pregnancy and lactation period
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About First Affiliated Hospital Of Chongqing Medical University
The First Affiliated Hospital of Chongqing Medical University is a leading academic medical center dedicated to advancing healthcare through innovative clinical research and education. As a prominent sponsor of clinical trials, the hospital is committed to conducting high-quality, ethically-driven studies that contribute to the understanding and treatment of various medical conditions. With a robust infrastructure and a team of experienced researchers and healthcare professionals, the institution fosters collaboration across disciplines to enhance patient care and improve health outcomes. Its strategic focus on translational medicine underscores the hospital's role in bridging the gap between laboratory discoveries and clinical applications, ultimately benefiting patients and the broader medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chongqing, Municipality Directly Under The Central Government, China
Patients applied
Trial Officials
Fei Xiao, Professor
Study Director
First Affiliated Hospital of Chongqing Medical University
Jing Luo, associate professor
Principal Investigator
First Affiliated Hospital of Chongqing Medical University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported