Comparison of RIMA-SVG and Ao-SVG Techniques in Coronary Artery Bypass Grafting

Launched by SECOND HOSPITAL OF JILIN UNIVERSITY · Jan 16, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two different surgical techniques used in coronary artery bypass grafting (CABG), which is a procedure to improve blood flow to the heart in patients with coronary artery disease. The two methods being compared are the RIMA-SVG technique, where the saphenous vein grafts (SVGs) are connected to the right internal mammary artery, and the Ao-SVG technique, where the SVGs are attached to the aorta. The goal is to see if the RIMA-SVG method helps the grafts work better and reduces complications after surgery.

To participate in this trial, you need to be between 18 and 80 years old and scheduled for your first CABG surgery that requires at least two SVGs. If you join, you will be randomly assigned to one of the two surgical groups and undergo the surgery while your heart is still beating. After the surgery, the trial will follow you for a year to check how well the grafts are working and to monitor for any complications, like infections or heart problems. This study aims to find out which surgical method may lead to better outcomes for patients undergoing this important procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged 18 to 80 years.
• • 2. Scheduled for their first planned coronary artery bypass grafting (CABG) with at least two sequential saphenous vein grafts (SVGs).
• • 3. Able and willing to provide written informed consent.
• Exclusion Criteria:
• • 1. Patients unable to provide written informed consent.
• • 2. Patients requiring other cardiac surgeries (e.g. valve replacement, congenital heart defect surgery, or aortic dissection repair).
• • 3. Patients with severe stenosis of the left or right subclavian artery.
• • 4. Patients for whom aortic clamping is infeasible due to calcification of the ascending aorta.
• • 5. Patients with bilateral SVG varicosities unsuitable for grafting.
• • 6. Patients with active malignancy.
• • 7. Patients with active bleeding or a history of bleeding tendency.
• • 8. Patients with previous intracranial hemorrhage, ischemic stroke within 14 days preoperatively, or severe carotid artery stenosis.
• • 9. Patients with severe hepatic dysfunction.
• • 10. Patients requiring emergency surgery.