Proteomic Analysis of Patients Undergoing Bariatric Surgery

Launched by UNIVERSIDADE FEDERAL DE PERNAMBUCO · Jan 16, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how proteins in the blood of obese patients change before and after they have bariatric surgery, which is a type of weight-loss surgery. Researchers believe that understanding these protein changes can help improve treatments for obesity and related health issues. The study will focus on patients who are significantly overweight, specifically those with a Body Mass Index (BMI) of over 35, or over 40 without other health problems.

To be eligible for this trial, participants need to be adults aged 18 and older who meet the BMI criteria mentioned. However, people with a history of cancer or certain other health conditions that increase cancer risk won't be able to join. The study is not yet recruiting participants, but those who do take part can expect to provide blood samples before and after their surgery to help researchers learn more about these important protein changes. This information could lead to better understanding and treatment options for obesity and its related conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients over 18 years of age with a BMI above 35 kg/m² associated with comorbidity or BMI above 40 kg/m² without comorbidities,
• Exclusion Criteria:
• • Patients with a previous history of cancer;
• • Underage patients
• • Patients with other diseases predisposing to the development of cancer: cirrhosis, ulcerative colitis, Barrett's esophagus, etc.
• • Patients who have previously undergone bariatric surgery;