Exploring Minor Proteins and Peptides in Human Milk: a Proteomic Analysis Across Lactation Stages
Launched by MAIMÓNIDES BIOMEDICAL RESEARCH INSTITUTE OF CÓRDOBA · Jan 16, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the different proteins and peptides found in human milk (HM) to understand how they support the healthy growth and development of newborns, especially those who are born low weight or preterm. Researchers will collect milk samples from breastfeeding mothers at three different stages after giving birth: early milk (colostrum), transitional milk, and mature milk. They aim to explore how the composition of these proteins changes based on the baby’s birth weight and gestational age, which is the length of the pregnancy.
To participate in the study, mothers need to be healthy and have had a monitored pregnancy at the Reina Sofía University Hospital in Córdoba. They should plan to exclusively breastfeed their newborns for at least the first four months. Unfortunately, mothers whose babies have certain medical conditions or those with complex pregnancy histories won't be eligible. By joining this study, participants can help researchers better understand how to improve nutrition for preterm and low-birth-weight infants, which could lead to better support for their growth and development.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Healthy mothers
- • With monitored pregnancies within the care area of the Reina Sofía University Hospital in Córdoba
- • With newborns expected to be exclusively breastfed until 4 months
- Exclusion Criteria:
- • Mothers whose newborns have any of the following conditions: congenital malformation, chromosomal abnormality, hypoxia-ischemia, gastroschisis, polycythemia, hypoglycemia, sepsis, blood incompatibility
- • Pathological pregnancy, pregnancy by in vitro fertilization, or multiple pregnancies
- • With no plan to exclusively breastfeed until 4 months
- • Under medical treatment
- • Have a drug addiction
- • Refuse informed consent
- • Have had previous breast surgery
- • Live outside the metropolitan area
About Maimónides Biomedical Research Institute Of Córdoba
The Maimónides Biomedical Research Institute of Córdoba is a leading research organization dedicated to advancing biomedical science through innovative clinical trials and translational research. Located in Córdoba, Spain, the institute focuses on a multidisciplinary approach to address pressing health challenges, fostering collaboration among researchers, clinicians, and industry partners. Its commitment to excellence in research is complemented by state-of-the-art facilities and a robust ethical framework, ensuring the highest standards of scientific integrity and patient safety. By prioritizing cutting-edge research and the development of novel therapeutic strategies, the Maimónides Biomedical Research Institute aims to contribute significantly to the improvement of global health outcomes.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Córdoba, , Spain
Córdoba, , Spain
Patients applied
Trial Officials
José Luis Gómez-Chaparro Moreno, MD, Ph.D
Principal Investigator
Maimonides Biomedical Research Institute of Cordoba (IMIBIC)
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported