Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

Launched by MOHAMED MAHER ISMAIL AHMED ELASHMAWY · Jan 17, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new treatment option for Dupuytren's contracture, a condition that causes the fingers to bend towards the palm, making it difficult to straighten them. The researchers want to see how effective and safe a procedure called ultrasound-guided needle knife dissection is for improving hand function compared to traditional surgery. This method uses ultrasound technology to guide a small knife to cut the thickened tissue in the hand, which may help reduce complications and recovery time.

To participate in the trial, you need to be diagnosed with Dupuytren's contracture and be willing to undergo this new treatment. However, if you have had previous surgery on the same hand, have an active infection or open wound, or have certain health conditions, you may not be eligible. If you join the study, you can expect to receive the ultrasound-guided procedure and be monitored for its effectiveness and safety. This trial is currently recruiting participants aged 65 to 74, and it's open to all genders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants diagnosed with Dupuytren's Contracture.
• • Willing to undergo ultrasound-guided needle knife dissection
• Exclusion Criteria:
• • Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
• • Active hand infections, open wounds, or dermatological conditions in the treatment area.
• • Coagulopathy or use of anticoagulant that cannot be safely paused
• • Neuromuscular disorders affecting hand function
• • Pregnancy or breastfeeding
• • Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
• • Known hypersensitivity to local anesthetics.