Enhanced Recovery After Urologic Surgery

Launched by XIAGUANG DUAN · Jan 17, 2025

Keywords

ClinConnect Summary

This clinical trial is designed to explore different methods of managing pain for patients undergoing various urological surgeries, such as circumcision, hernia repair, and prostate procedures. The main goal is to see if these pain management techniques—like using an epidural, a specific type of nerve block, or patient-controlled pain relief—can reduce the need for opioid medications after surgery. The trial will also look at the safety of two local anesthetics, liposomal bupivacaine and ropivacaine, to ensure they are safe for patients.

To participate, individuals of any age who are scheduled for one of these urological surgeries and meet certain health criteria can join. They should not have bleeding disorders, infections, or severe health issues that could complicate the study. Participants will receive one of the pain management options and will be monitored closely after their surgery to assess their pain levels, overall recovery, and satisfaction with the pain relief they received. This study aims to find better ways to help patients manage pain after surgery, which can lead to quicker recoveries and less reliance on strong pain medications.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • any age.
• • American Society of Anesthesiologists (ASA) physical status classification of I-III.
• • undergo urological surgery.
• • receive one of the following analgesic techniques: epidural analgesia (EA), paravertebral block (PVB), transversus abdominis plane (TAP) block, intravenous patient-controlled analgesia (PCA), or intrathecal morphine.
• • provided voluntary informed consent.
• Exclusion Criteria:
• • a bleeding disorder or coagulopathy.
• • infection at the intended puncture site or systemic infection.
• • a known allergy to local anesthetics.
• • spinal deformity or spinal injury.
• • a psychiatric disorder that could impair their ability to cooperate with the study protocol.
• • pregnant or breastfeeding.
• • severe cardiovascular or pulmonary dysfunction.
• • chronic opioid use (defined as \>1 month) at high doses.