Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgery: a Randomized Controlled Trial

Launched by CHINA NATIONAL CENTER FOR CARDIOVASCULAR DISEASES · Jan 19, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at two techniques—remote ischemic preconditioning and transcranial electrical stimulation—to see if they can help prevent neurological complications that sometimes happen during heart surgery. These complications can lead to serious problems like disability or even death, so the researchers want to find out if these methods are effective and safe for patients who are at high risk. Participants in the study will either receive these treatments or a placebo (a "dummy" treatment) twice a day for three days before their surgery.

To be eligible for this trial, participants need to be between 18 and 80 years old and scheduled for elective heart surgery. They should also have a history of heart disease and be considered at high risk for neurological issues after surgery, which might include having had a previous stroke or certain artery conditions. After the surgery, participants will take part in follow-up assessments to monitor their recovery. The trial is not yet recruiting, but it’s an important step toward improving safety and outcomes for patients undergoing cardiac procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age range: 18-80 years old;
• • 2. Surgical patients with heart disease;
• • 3. Elective surgery;
• • 4. Patients identified as high-risk for postoperative neurological complications; Previous stroke history; Moderate to severe stenosis of the head and neck arteries was evaluated;
• • 5. Be able to understand and comply with the requirements of clinical trial protocols, and voluntarily sign informed consent forms.
• Exclusion Criteria:
• • -