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Search / Trial NCT06794827

Early-access Avacopan in Real-world ANCA-associated Vasculitis

Launched by LEIDEN UNIVERSITY MEDICAL CENTER · Jan 22, 2025

Trial Information

Current as of June 06, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at the use of a medication called avacopan for patients with ANCA-associated vasculitis, a condition that affects the blood vessels and can harm different organs in the body. The researchers want to understand how avacopan is being used in real-world settings across Europe, particularly focusing on how patients respond to this treatment and the characteristics of those who receive it. By gathering this information, the study aims to improve the way avacopan is used and potentially fill in gaps in our understanding of this medication.

To be part of this trial, participants need to have been diagnosed with either Granulomatosis with Polyangiitis (GPA) or Microscopic Polyangiitis (MPA) and should be starting treatment with avacopan. The study is open to adults aged 16 and older. Participants will be asked to provide consent for their medical data to be used in the research, and they can expect to share their experiences and outcomes while being treated with avacopan. This trial is currently recruiting participants and hopes to gather valuable insights that could help improve treatment for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Established diagnosis of GPA or MPA
  • Treatment (initiation) with avacopan
  • Informed consent for use of medical data
  • Exclusion Criteria:
  • If there is no AAV disease activity present that can be supported by an objectifiable clinical measure or assessment
  • If a subject is below 16 years old

About Leiden University Medical Center

Leiden University Medical Center (LUMC) is a prominent academic medical center located in the Netherlands, renowned for its commitment to advancing healthcare through innovative research and high-quality patient care. As a clinical trial sponsor, LUMC focuses on translating scientific discoveries into effective therapies, fostering collaborations between researchers, clinicians, and industry partners. The center is dedicated to conducting rigorous clinical studies across various medical fields, ensuring adherence to ethical standards and regulatory requirements while prioritizing patient safety and outcomes. Through its multidisciplinary approach, LUMC aims to contribute significantly to the understanding and treatment of complex health conditions, driving progress in personalized medicine and improving global health.

Locations

Leiden, Zuid Holland, Netherlands

Patients applied

0 patients applied

Trial Officials

Y.K. Onno Teng

Principal Investigator

Leiden University Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported