Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults

Launched by NEW YORK UNIVERSITY · Jan 22, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how surgical weight loss, known as bariatric surgery, might help improve chronic widespread pain in adults who identify as Hispanic/Latino or Black/African American and have a higher body mass index (BMI). The researchers want to find out if people's pain at rest and when moving improves after the surgery, and if their ability to manage pain and joint function changes as well. Participants will be assessed before the surgery and again six months after to see how their pain and physical abilities have changed.

To be eligible, you must identify as Black/African American or Hispanic/Latino, be eligible for bariatric surgery (meaning you have a BMI of 40 or higher, or 35 with related health issues), and have chronic widespread pain in multiple areas of your body. You should also be able to speak English or Spanish, and walk independently or with a cane. If you choose to participate, you will help researchers understand the relationship between weight loss and pain improvement, which could lead to better treatment options for others in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Self-identify as Black/African American or Hispanic/Latino ethnicity based on the U.S Census racial categories
• • Eligible candidates for bariatric surgery (BMI greater than or equal to 40 or BMI greater than or equal to 35 with comorbidity
• * Meets criteria for chronic widespread pain (CWP) based on the following:
• • 1. self-reported pain at 3 or more anatomical sites
• • 2. painful regions on both sides of the body
• • 3. self-reported pain intensity at rest of 3 out of 10 or higher using the Numeric Pain Rating Scale (NPRS) or equivalent
• • Conversational language fluency in English or Spanish
• • Able to give voluntary, written informed consent to participate
• • Able to walk independently or with a cane prior to study enrollment
• Exclusion Criteria:
• • Prospective participants with a previous history of bariatric surgery
• • Have acute pain (pain for less than 6 weeks) at 1 month prior to study enrollment
• • Have a systemic autoimmune disorder or immunodeficiency
• • Have an unstable psychological condition
• • Are non-ambulatory or ambulate with an assistive device other than a cane
• • Pain localized to surgical sites at 3 months post-surgery