Monaco-Serial Biological Function K-value Index Constraint for Cardiac Dose

Launched by JIANJUN LAI · Jan 26, 2025

Keywords

ClinConnect Summary

The Monaco-Serial clinical trial is studying a new way to plan radiotherapy for women with left-sided breast cancer. Radiotherapy is an important treatment for breast cancer, but it can sometimes harm the heart, especially when the radiation is directed near this vital organ. This trial aims to find the best settings in the Monaco radiotherapy system to minimize radiation exposure to the heart while effectively treating the breast. By using a technique called deep inspiration breath-hold (DIBH), patients can take a deep breath and hold it during treatment, which helps move the heart further away from the area being treated. The trial will analyze data from 51 women who have already undergone this treatment to see how different settings affect radiation doses to the heart and other organs.

To be eligible for this trial, participants must be women who have completed DIBH-IMRT radiotherapy for left-sided breast cancer. The study is not yet recruiting participants, but once it starts, eligible women can expect to contribute to research that could improve future radiotherapy planning and reduce the risk of heart damage during treatment. This trial is important because it could help doctors find the safest and most effective ways to treat breast cancer while protecting patients' hearts.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • The patients who have successfully completed left-sided breast cancer DIBH-IMRT radiotherapy.
• Exclusion Criteria:
• • The patients who have not completed left-sided breast cancer DIBH-IMRT radiotherapy.