BiomeBakery Project

Launched by UNIVERSITY OF READING · Jan 22, 2025

Keywords

ClinConnect Summary

The BiomeBakery Project is a research study that aims to understand how a special type of bread, enriched with prebiotic fiber, might help improve thinking skills, mood, and inflammation in healthy adults aged 60 to 75 who have some mild to moderate issues with memory or mental clarity. The researchers want to see if eating this bread regularly can make a positive difference in various health aspects for older adults who often consume bread.

To be part of this study, participants need to be between 60 and 75 years old, have normal vision and hearing, and should have a normal body weight. They should also eat bread at least five times a week and experience some cognitive difficulties. However, people with certain health conditions, allergies, or who take specific medications will not be able to join. If chosen, participants will receive the prebiotic bread to eat regularly and will be monitored to see how it affects their thinking, mood, and overall health. It's a great opportunity to contribute to research that could help improve health in older adults!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aging between 60-75 years old
• • Having normal vision and hearing
• • Having a normal body mass index (BMI\<30)
• • Having mild to moderate subjective cognitive complaints
• • Consuming bread (5 or more times a week)
• Exclusion Criteria:
• • Smoking
• • Having food allergies
• • Following restrictive and/or unbalanced diets
• • Changing dietary intake majorly in past month
• • Being diagnosed with any psychiatric or neurologic conditions (e.g. schizophrenia, depression, dementia) including eating disorders
• • Being diagnosed with any cardiometabolic diseases (including type II diabetes and cardiovascular disease), or suffering from hypertension or thrombosis related disorders or suffer from thyroid disease
• • Being anaemic
• • Currently taking anticoagulants, antiplatelet medication, antidepressants, proton-pump inhibitors
• • Currently consuming prebiotic or probiotic supplements
• • Continuous antibiotic use for \> 3 days within 1 month prior to enrolment
• • Continuous use of weight-loss drug for \> 1 month before screening
• • Having a significant gastrointestinal (GI) condition affecting absorption including (but not limited to) inflammatory bowel disease; total colectomy or bariatric surgery; irritable bowel disease; end stage renal disease; active cancer, or treatment for any cancer, in last 3 years
• • Having a high fibre intake defined as \> 20g of fibre/day
• • Wheat and/or gluten intolerance and having coeliac disease