Effect of the Stellate Ganglion Block on the Retinal Microcirculation
Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Jan 27, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of a procedure called the stellate ganglion nerve block on the tiny blood vessels in the retina, which is the light-sensitive layer at the back of the eye. This procedure is often used to help manage severe pain but may also lower the activity of the sympathetic nervous system, which can become overactive during serious brain injuries, like hemorrhages (bleeding in the brain). Researchers want to see if this nerve block can improve blood flow in the retina by comparing images taken before and after the procedure.
To participate in this trial, you need to be at least 18 years old and scheduled to receive the stellate ganglion nerve block for a medical reason, such as complex regional pain syndrome. Unfortunately, if you are pregnant, do not speak English, or have a physical condition that makes it hard to sit up and look into an imaging device, you won’t be eligible. For those who qualify, the study will involve simple eye imaging before and after the nerve block, helping us understand its impact on the retinal blood vessels.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age 18 years or older
- • Patients receiving the stellate ganglion nerve block for an approved indication, e.g. complex regional pain syndrome
- Exclusion Criteria:
- • Pregnancy
- • Non-English speaking
- • Temporary or permanent physical limitation that renders the patient unable to sit up and look inside OCTA device
About University Of Texas Southwestern Medical Center
The University of Texas Southwestern Medical Center is a leading academic medical institution dedicated to advancing healthcare through innovative research, education, and clinical excellence. With a strong emphasis on translational medicine, the center conducts cutting-edge clinical trials aimed at developing novel therapies and improving patient outcomes across a wide range of diseases. Its multidisciplinary approach leverages a collaborative network of renowned faculty, state-of-the-art facilities, and a commitment to ethical research practices, positioning UT Southwestern at the forefront of medical discovery and patient care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dallas, Texas, United States
Patients applied
Trial Officials
Noah Jouett, DO, PhD
Principal Investigator
UT Southwestern Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported