Optical Coherence Tomography Angiography in Neurological Disease

Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Jan 27, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a special imaging technique called Optical Coherence Tomography Angiography (OCTA), which uses near-infrared light to take pictures of the blood vessels in the eye. Researchers want to see how well OCTA can help identify problems in the brain, especially in patients who have experienced conditions like strokes or bleeding in the brain. By comparing the OCTA images of patients with these neurological issues to those of healthy individuals, the team hopes to gather important information that could lead to more research in this area.

To participate in this study, individuals must be 18 years or older and have been admitted to the neuroscience intensive care unit for certain conditions, such as subarachnoid hemorrhage or ischemic stroke. However, pregnant women, non-English speakers, and those who cannot follow simple commands will not be eligible. Participants can expect to undergo OCTA imaging while sitting comfortably, and their involvement will help advance understanding of neurological diseases and improve future treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18 years or older
• • Patient admitted to the neuroscience intensive care unit with a diagnosis of: subarachnoid hemorrhage, intracerebral hemorrhage, intracranial aneurysm (ruptured or unruptured), intracranial vascular malformation, ischemic stroke, seizure disorder, intracranial infection, intracranial tumor(s), inflammatory demyelinating disease, traumatic brain injury and/or neuromuscular respiratory failure OR subjects from the community without major neurologic, cardiovascular, pulmonary or metabolic disease
• Exclusion Criteria:
• • Pregnancy
• • Non-English speaking
• • GCS motor score less than 6 (i.e. must be able to follow commands)
• • Temporary or permanent physical limitation that renders the patient unable to sit up and look inside OCTA device