Treatment of Periodontal Intrabony Defects With Liquid Platelet-Rich Fibrin Mixed With Denaturated Albumin Gel (ALB_PRF)
Launched by MANSOURA UNIVERSITY · Jan 22, 2025
Trial Information
Current as of July 24, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
28 patients will be selected from the outpatient clinic in the Oral Medicine and Periodontology Department, Faculty of Dentistry, Mansoura University according to Pre-operative CBCT that will be used to evaluate the bone destruction pattern.
Sample size will be calculated using G-Power 3.1 for Mac with (α = 0.05, and power = 0.95). One-way ANOVA test will be used and effect size of (0.7) based on the anticipated mean difference of the efficacy of new generation platelet-rich fibrin according Nagy et.al 2021. The total sample size of the four groups will be 28 patients.
Inclusion criteria:...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Periodontist stage III according to classification of periodontal and peri-implant disease and conditions (2018).
- • Patient with two or three walls or combined bony defect.
- • Favourable pattern of occlusion.
- • Patient ability to comply with the required recall visits.
- Exclusion Criteria:
- • Local or systemic diseases that contraindicate surgery.
- • Smokers
- • Patients with parafunctional habits.
- • Pregnancy or lactation.
- • Diabetic patient.
- • Osteoporosis.
- • Immune-suppressed condition that may affect the outcome of the therapy.
About Mansoura University
Mansoura University is a prestigious academic institution located in Egypt, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, it leverages its extensive resources and expertise in various fields of healthcare to facilitate innovative research initiatives aimed at improving patient outcomes. The university collaborates with a network of healthcare professionals and researchers to conduct high-quality clinical trials, focusing on addressing critical health challenges through rigorous scientific methodologies. Its dedication to ethical research practices and adherence to regulatory standards underscores its role as a leader in the medical research community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Mansoura, , Egypt
Patients applied
Trial Officials
Dhaidan Naif Alshammari, Bachelor
Principal Investigator
faculty of dentistry Mansoura university
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported