Role of Menopause in Thermoregulation

Launched by PENN STATE UNIVERSITY · Jan 22, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how menopause affects the body’s ability to handle heat, especially in women aged 42 to 64. As people get older, their bodies don’t respond to heat as well, which can be risky, especially for women after menopause. Researchers want to understand how lower levels of estrogen, a hormone that decreases after menopause, combined with aging, influence how women manage heat stress.

To be eligible for this study, women need to be between 42 and 64 years old. However, those with certain health issues, like inflammatory bowel diseases or heart problems, or who are using hormone therapy or contraceptives, will not be able to participate. Participants in the study will help researchers learn more about the effects of menopause on heat regulation, which could lead to better health recommendations for women as they age.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women ages 42-64
• Exclusion Criteria:
• • Chron's disease, diverticulitis, or similar gastrointestinal disease
• • Abnormal resting exercise electrocardiogram (ECG)
• • Tobacco use
• • High-risk determined by the Atherosclerotic Cardiovascular Disease (CVD) Risk Factor
• • Assessment
• • Using hormone therapy
• • Using hormonal contraceptives