EFFECT OF PYRAMIDAL TRAINING ON EPICARDIAL FAT FOR CORONARY ARTERY DISEASE PREVENTION
Launched by CAIRO UNIVERSITY · Jan 23, 2025
Trial Information
Current as of July 01, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating how a specific type of exercise program, called pyramidal training, can help prevent coronary artery disease, particularly in women with class I obesity. The study will look at various health factors, including epicardial fat (the fat around the heart), body mass index (BMI), waist circumference, cholesterol levels, quality of life, and adherence to a Mediterranean diet, which is known for its heart-healthy benefits.
To participate, women aged 30 to 40 years old with a BMI between 30 and 34.9 and a larger waist circumference (over 88 cm) may be eligible. They should also have certain cholesterol issues, like high total cholesterol or low levels of good cholesterol. However, women with certain health problems, like serious heart issues, respiratory diseases, or cognitive impairments, will not be included in the trial. Participants can expect to engage in the exercise program while tracking their health improvements over time, contributing valuable information to help understand how exercise may benefit heart health.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Fifty females' patients with class I obesity (BMI 30 to 34.9 kg/m2, Waist circumference \> 88 cm).
- • Their age ranges from 30-40 years old.
- • Dyslipidemia and lipid profile as follow (total cholesterol high: 240 mg/dl, HDL less than 40 mg/dl, LDL high: 160-189 mg/dL and triglycerides high: 200-499 mg/dl).
- • All patients will be clinically and medically stable when attending the study.
- Exclusion Criteria:
- * Patients with conditions will be excluded such as:
- • Musculoskeletal problems.
- • Chronic pulmonary disease.
- • Missed more than two weeks of the program or want to terminate the program.
- • Unstable angina.
- • Acute illness.
- • Uncontrolled cardiac arrhythmia.
- • Decompensated heart failure.
- • Cognitive impairment or mental disorders.
- • Systolic blood pressure higher than 180, and/or diastolic blood pressure over 100mmHg.
- • DVT.
- • Multiple food allergies/intolerances or gastrointestinal difficulties of the prescribed diet.
- • Cancer (have special nutritional and training needs).
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, Giza, Egypt
Patients applied
Trial Officials
Zeinab M Helmy, Professor
Study Chair
Cairo University
Ebtesam N Abdel-Mohsen, PhD
Study Director
Cairo University
Hoda A Saad ELDin, PhD
Study Director
Alexandria University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported