Radiological Diagnostics in Patients With Deep Endometriosis

Launched by IRCCS AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA · Jan 28, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a condition called deep endometriosis, which occurs when tissue similar to the lining inside the uterus grows outside of it, affecting various organs in the lower abdomen. The research aims to improve the diagnosis and treatment planning for women with deep endometriosis, particularly using advanced imaging techniques like MRI. It is important because while surgery can help reduce symptoms and improve fertility, it can also lead to complications affecting the bladder, bowel, and sexual function. This trial is exploring a surgical approach that aims to avoid damaging the nerves in these areas, which could lead to better outcomes for patients.

To be eligible for the trial, participants must be women aged 18 to 40 who have been diagnosed with deep endometriosis and are considering laparoscopic surgery (a minimally invasive surgical technique). However, those with a history of certain medical conditions, prior abdominal surgeries, or previous cancers cannot participate. If enrolled, participants can expect to undergo MRI scans to help guide their treatment and may receive specialized surgical care aimed at minimizing complications. This trial is currently recruiting, and it represents a step forward in understanding and treating deep endometriosis more effectively.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Clinical and ultrasound diagnosis of deep endometriosis, with or without ovarian endometriosis, with indication for MRI for further diagnosis and subsequent candidate for laparoscopic surgical treatment of the pathology
• • Age between 18 and 40 years
• • Obtaining informed consent
• Exclusion Criteria:
• • Previous abdominal surgery
• • Personal history of malignancy (current or previous)
• • Chronic inflammatory bowel disease (Crohn's disease, Ulcerative Rectocolitis, Indeterminate Colitis), interstitial cystitis
• • Personal history of Pelvic Inflammatory Disease (PID), active or previous
• • Previous radiotherapy/chemotherapy
• • Radiculopathy, herniated discs, spinal abnormalities and pathologies
• • Laparotomic conversion during surgery