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Search / Trial NCT06801522

Adrenaline Nasal Pack vs Xylometazoline Nasal Drops During Nasotracheal Intubation

Launched by SHAHEED MOHTARMA BENAZIR BHUTTO INSTITUE OF TRAUMA · Jan 24, 2025

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Nasal Bleeding, Nasotracheal Intubation, Adrenaline Pack, Xylometazoline Nasal Drops

ClinConnect Summary

This clinical trial is studying two different treatments to help reduce nasal bleeding during a medical procedure called nasotracheal intubation, which is often needed for certain surgeries in the mouth and jaw area. The trial is comparing xylometazoline nasal drops, which help shrink blood vessels in the nose, to adrenaline nasal packing, which involves placing a special packing in the nose to control bleeding. The main goal is to find out which treatment works better at minimizing nasal bleeding during the procedure.

To be eligible for this trial, participants must be between 18 and 60 years old and have a specific classification of their airway (Mallampati score 1 or 2), indicating that their airway is relatively easy to manage. Participants should also be in good health, without serious conditions like uncontrolled high blood pressure or a history of nasal problems. Those who join the study will be randomly assigned to receive either the nasal drops or the packing, and their experiences will help researchers understand which method is more effective for reducing nasal bleeding during surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • ASA 1 and 2
  • Age group between 18-60 years
  • Mallampati score 1 and 2
  • Either gender
  • Participants who undergo elective oromaxillofacial surgery
  • Exclusion Criteria:
  • Lack of consent
  • Participants with anticipated difficult airway
  • Participants receiving anticoagulant therapy
  • History of nasal abnormality (nasal surgery, trauma, polyp, obstruction)
  • History of repeated epistaxis
  • History of uncontrolled hypertension, diabetes, pregnancy, and any other cardiac or cerebral events.

About Shaheed Mohtarma Benazir Bhutto Institue Of Trauma

The Shaheed Mohtarma Benazir Bhutto Institute of Trauma is a premier healthcare institution dedicated to the advancement of trauma care and research. Located in Karachi, Pakistan, the institute focuses on providing high-quality medical services while fostering clinical trials aimed at improving trauma management and patient outcomes. With a commitment to innovative research and collaboration, the institute plays a pivotal role in enhancing medical knowledge and practices in the field of trauma care, contributing significantly to both local and international healthcare standards.

Locations

Karachi, Sindh, Pakistan

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported