Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes

Launched by LILLE UNIVERSITY · Jan 27, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how different types of exercise—both continuous moderate exercise and intense intermittent exercise—affect blood sugar levels in adolescents with type 1 diabetes. Researchers want to understand how the time of day (circadian rhythm) influences these effects. The trial is currently looking for participants aged 10 to 16 who have been living with type 1 diabetes for at least a year and have good control of their blood sugar, as indicated by an HbA1c level of 12% or lower.

If your child is eligible and decides to participate, they will engage in various exercise routines while researchers monitor their blood sugar levels. Participation involves some procedures and commitments, but the research is designed to have minimal risks. It's important to note that children with certain medical conditions or complications related to diabetes may not be able to join. This trial aims to gather important information that could help improve exercise recommendations for young people living with diabetes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children and adolescents aged 10 to 16;
• • Living with type 1 diabetes for at least 1 year with HbA1c less than or equal to 12%;
• • Socially insured ;
• • Having given their written consent to participate in the research, as well as that of their legal guardians;
• • Willing to comply with all research procedures and duration.
• Exclusion Criteria:
• • Clinically significant microvascular complications: nephropathy (estimated glomerular filtration rate less than 40 ml/min), neuropathy or severe proliferative retinopathy as assessed by the investigator;
• • Recent acute macrovascular event (\< 3 months), e.g. acute coronary syndrome or cardiac surgery;
• • Abnormal blood picture and/or anemia;
• • Current pregnancy;
• • Other serious medical condition likely to interfere with study participation or ability to complete exercise periods in the judgment of the investigator (e.g., orthopedic limitation);
• • Inability to receive informed information;
• • Inability to participate in the entire study;
• • Lack of social security coverage;
• • Refusal to sign consent form.