Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis

Launched by FUTURE UNIVERSITY IN EGYPT · Jan 27, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of two different medications—selenium and calcium hydroxide—in treating infected teeth (specifically, the mandibular first molars) that have a condition called necrotic pulp with symptomatic apical periodontitis. The goal is to see which medication better helps reduce pain after dental procedures and fight bacteria inside the tooth. Selenium is a mineral that might help improve the immune response, while calcium hydroxide has been traditionally used to kill bacteria. The trial will include 60 patients, divided into three groups: one group will receive selenium alone, another group will receive selenium with calcium hydroxide, and the third group will serve as a control.

To participate in this study, you must be between the ages of 20 and 40 and have a specific dental condition affecting your mandibular first molars. You should be in good health, without any serious medical issues, and able to provide consent to take part in the study. Those with certain exclusions, like pregnant women or people with specific dental problems, will not be eligible. If you decide to participate, you can expect to receive one of the two medications during your dental treatment and be monitored for pain and healing afterward. This trial aims to find a better way to manage dental infections and improve recovery, which could help many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Medically free patients with no systemic disease: (American Society of Anesthesiologists / (ASA Class I or II).
• • Age range is between 20 to 40 years.
• • No sex predilection.
• • Patients having necrotic pulp with symptomatic apical periodontitis in mandibular first molars.(type l distal root canal ) .
• • Sensitive to percussion.
• • Periapical radiographic appearance of teeth showed slight widening in lamina dura.
• • restorable teeth.
• • Positive patient"s acceptance for participating in the study.
• • Patients able to sign informed consent.
• Exclusion Criteria:
• • Medically compromised patients.
• • Pregnant or lactating females.
• • Psychologically disturbed patients.
• • Patients with a history of allergy to any medication used in the study were excluded.
• • If anti-inflammatory analgesics or antibiotics have been administrated by patient during the past 12 hours preoperatively.
• • Patients with swelling or acute peri-apical abscess or fistulous tract.
• Teeth that have:
• • Wide or open apex.
• • Vital pulp tissues.
• • Periodontally affected with grade 2 or 3 mobility.
• • Not restorable teeth.
• • Abnormal anatomy and calcified canals.
• • Previous root canal treatment.