Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management

Launched by OSOIAN CRISTIANA · Jan 27, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how a special monitoring tool called the Nociception Level Index (NOL) can help manage pain during major abdominal surgeries. The researchers want to see if using NOL can lead to a reduction in the amount of opioid medications needed during and after surgery, especially when combined with an intravenous medication called lidocaine that may also help with pain relief. They believe that this approach could improve recovery in the first 24 hours after surgery by reducing the need for stronger pain medications.

To participate in the trial, individuals must be over 18 years old and have specific types of surgeries related to certain cancers of the stomach, liver, or pancreas. Participants will not be eligible if they are pregnant, have chronic pain conditions, or are taking medications that could affect the study's results. Those who join the study can expect to receive careful monitoring and pain management during their surgery, with the hope of having a more comfortable recovery experience.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age \> 18 years
• • ASA score I-III
• • surgery for gastric or hepatobiliary or pancreatic neoplasia
• Exclusion Criteria:
• • pregnancy
• • lactation
• • neuraxial or regional anesthesia
• • chronic treatment with drugs that can influence autonomic nervous system
• • diuretics or nitroglycerin administration on the day of surgery
• • severe neurological disability
• • severe hemodynamic instability
• • chronic pain
• • chronic opioid treatment
• • allergy to any of the study drugs
• • severe untreated disease or organ failure
• • pacemaker
• • emergency surgery
• • patient refusal to participate