Construction of a Model for the Differential Diagnosis of SArcoma/myoma Based on the RAdiomics Features: Single-center Observational Study

Launched by IRCCS AZIENDA OSPEDALIERO-UNIVERSITARIA DI BOLOGNA · Jan 28, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help doctors tell the difference between two types of uterine growths: uterine sarcoma, which is a rare and aggressive cancer, and uterine myoma, which is a common benign (non-cancerous) condition. The goal is to use a technique called radiomics, which analyzes medical images to gather detailed information about these growths, potentially improving how doctors diagnose them before surgery. This could help in deciding the best treatment for patients based on their specific condition.

To participate in this study, women aged 18 to 80 who have been diagnosed with either uterine sarcoma or myoma may be eligible. They should have a pre-operative CT scan done within 30 days of surgery. Participants will need to give their consent to join the study and be followed up at the clinical center. It's important to note that if a patient's CT images are of low quality or if they have other active cancers, they won’t be able to take part in the trial. By joining, participants may contribute to improving the understanding and treatment of these uterine conditions.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Histological diagnosis of uterine sarcoma or myoma
• • Patients with pre-operative CT performed for diagnostic suspicion no more than 30 days before surgery
• • Age between 18 and 80 years
• • Patients followed in the clinical care path in our center
• • Obtaining informed consent
• Exclusion Criteria:
• • Low quality of CT images.
• • Patients affected by other active neoplasms or diagnosed less than 5 years before the diagnosis of uterine sarcoma or myoma.