Analysis of Influencing Factors of High-Order Aberrations of SMILE with Lenticule Retained

Launched by SECOND AFFILIATED HOSPITAL OF NANCHANG UNIVERSITY · Jan 30, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at factors that might affect the quality of vision after a specific eye surgery called SMILE (Small-incision Lenticule Extraction). This surgery is designed to correct vision problems, particularly nearsightedness. Researchers want to understand how certain conditions or characteristics might influence the clarity of vision after the procedure, especially when some of the eye tissue is left in place.

If you're an adult aged 18 or older, have stable nearsightedness that hasn't changed for at least two years, and meet other health criteria, you might be eligible to participate in this study. Participants will need to sign a consent form and attend follow-up appointments as part of the study. It's important to know that certain eye conditions and health issues, like diabetes or severe mental disorders, may exclude someone from joining. If you choose to participate, you will be contributing to research that could help improve the outcomes of this type of eye surgery for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age ≥ 18 years, gender unrestricted;
• • 2. Equivalent spherical refraction ≤ -10.0D, corrected distance visual acuity ≥ 1.0, myopia stable for ≥ 2 years, and no contact lens wear for at least 2 weeks;
• • 3. The patient voluntarily participates in this study, signs the informed consent form, and agrees to follow up according to the study plan;
• • 4. Predicted postoperative residual corneal stromal thickness ≥ 280 micrometers.
• Exclusion Criteria:
• • 1. Subclinical keratoconus, keratoconus, moderate to severe corneal opacities or scars, and other ocular conditions;
• • 2. Diabetes, keloid-prone constitution, autoimmune and connective tissue diseases, etc.;
• • 3. Severe mental disorders such as generalized anxiety disorder, panic disorder, depression, schizophrenia, and bipolar disorder; inability to cooperate with physicians;
• • 4. Refusal to participate in the study.