Effects of Tranexamic Acid Irrigation on Impacted Third Molar Surgery

Launched by BEZMIALEM VAKIF UNIVERSITY · Jan 31, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a medication called tranexamic acid (TXA) during the removal of impacted third molars, commonly known as wisdom teeth. TXA is used to help reduce bleeding during surgery, which can make the procedure safer and decrease the need for blood transfusions. The trial is currently looking for healthy individuals between the ages of 14 and 40 who need to have their impacted wisdom teeth extracted. To be eligible, participants should not have any bleeding disorders or significant health issues.

If you decide to participate, you will receive TXA during your surgery to see if it helps minimize bleeding. Most people tolerate TXA well, but like any medication, it can cause some mild side effects such as nausea or diarrhea. The trial aims to ensure that using TXA in this way is safe and effective, especially since it can be applied directly at the surgery site rather than through an injection. This method may lower the risk of serious complications. Overall, this study could help improve the safety and comfort of wisdom tooth extractions for many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Indicated for the Extraction of Bilaterally Impacted Third Molars with Bone Retention.
• • 2. Systemically healthy patients aged 14-40 years with no bleeding disorders.
• Exclusion Criteria:
• • 1. Patients with systemic diseases affecting general health.
• • 2. Patients diagnosed with any bleeding disorder.
• • 3. Patients with advanced infection or cysts associated with the impacted tooth.