Difference in Serum Estrogen Level Based on Methods of Vaginal Estrogen Application (fingertip Vs Applicator Use) in Post-menopausal Women

Launched by WALTER REED NATIONAL MILITARY MEDICAL CENTER · Jan 31, 2025

Keywords

ClinConnect Summary

This clinical trial is designed to understand how different methods of applying vaginal estrogen cream affect hormone levels in postmenopausal women. Specifically, the study compares using a fingertip versus an applicator to apply the cream, which is often used to treat conditions like vaginal dryness and discomfort after menopause. Researchers will also assess how satisfied women are with each application method through a questionnaire.

To participate in this trial, women need to be postmenopausal for at least one year and able to self-apply the cream using both methods. They should speak English and not be currently using other hormone therapies. The study is not yet recruiting participants, but once it starts, eligible women will have the chance to contribute to important research that could improve treatment options for many others.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • patients who are postmenopausal for at least 1 year (since their last menses)
• • patients who qualify for treatment with vaginal estrogen cream and are willing to complete the treatment
• • English speaking patients
• • patients should be able to self-apply the vaginal estrogen cream using the applicator method and the fingertip application
• • Patients who are surgically menopausal
• • Military healthcare beneficiary status
• Exclusion Criteria:
• • pre and perimenopausal women
• • contraindication to estrogen therapy (Deep vein thrombosis, history or active cancer)
• • women who are not able to self apply the vaginal estrogen cream
• • vaginal bleeding of unknown origin
• • women currently on hormone replacement therapy or vaginal estrogen therapy