Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis

Launched by ANKARA CITY HOSPITAL BILKENT · Jan 29, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a method called Transversus Abdominis Plane (TAP) block to see if it can help reduce pain for patients with acute appendicitis who need emergency surgery. The TAP block is a type of pain relief technique that involves injecting medication into a specific area of the abdomen before surgery. The goal of the study is to find out if this approach can make patients feel more comfortable and manage their pain better while they await surgery.

To participate in this trial, patients must be at least 18 years old and have been diagnosed with acute appendicitis, confirmed through tests like ultrasound or a CT scan. They should also be scheduled for surgery and able to give written consent to join the study. However, certain people are not eligible, including those with allergies to local anesthetics, specific medical conditions, or those who are pregnant. Participants can expect to receive pain management through the TAP block method and will help researchers learn more about how to improve care for patients with acute appendicitis in emergency situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients diagnosed with acute appendicitis in the emergency department and scheduled for definitive surgery following general surgical consultation: patients will have their Alvarado score calculated based on history, physical examination, and laboratory tests, and acute appendicitis will be confirmed by ultrasound and/or contrast-enhanced/non-contrast-enhanced abdominal CT.
• • Patients aged 18 and over
• • Patients who provide written consent
• Exclusion Criteria:
• • Patients with abdominal wall anatomical abnormalities
• • Patients with known local anesthetic allergies
• • Body mass index \> 30
• • Patients weighing less than 45 kg
• • Coagulopathy
• • Patients with opioid, alcohol, or substance addiction
• • Patients with skin infections at the site of local anesthetic application
• • Pregnant or breastfeeding patients
• • Hemodynamically unstable patients
• • Patients with liver or kidney failure
• • Patients with chronic pain disorders
• • Patients who have difficulty cooperating or have language barriers
• • Patients who do not provide written consent
• • Patients under 18 years of age