Evaluation of Sex Differences in Glucose Metabolism in Response to Sleep Curtailment

Launched by BRIGHAM AND WOMEN'S HOSPITAL · Jan 30, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how lack of sleep affects the way our bodies process sugar, also known as glucose metabolism, and whether this impact is different for men and women. Researchers want to understand if not getting enough sleep can lead to issues with how our bodies handle glucose, which is important for energy and overall health.

To participate in this study, you need to be a healthy adult who doesn't smoke, has regular sleep patterns, and can stay in the lab for 10 days and nights over two separate visits. Women participants should have regular menstrual cycles. The study is not looking for people with any history of sleep disorders, mental health issues, or those who take certain medications. If you join, you'll help researchers learn more about the effects of sleep on health, and your participation could contribute to important discoveries regarding sleep and metabolism.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy adults with conventional sleep-wake timing
• • Non-smokers
• • Completion of medical, psychological, and sleep screening tests
• • Able to spend 5 consecutive days/nights in the laboratory on two separate occasions (total of 10 days/nights in the laboratory)
• • Women must have a recent history of regular menstrual cycles
• Exclusion Criteria:
• • History of neurological or psychiatric disorder
• • History of sleep disorder or regular use of sleep-promoting medication
• • Current prescription, herbal, or over-the-counter medication use including hormonal birth control
• • Traveling across 2 or more time zones within past 3 months
• • Donating blood within past 8 weeks
• • Worked night or rotating shift work within past year
• • Hearing impairment, visual impairment
• • History of eye trauma or surgery
• • Drug or alcohol dependency