Association of EEG Parameters with Postoperative Delirium in Patient's with Parkinson's Disease
Launched by LONDON HEALTH SCIENCES CENTRE RESEARCH INSTITUTE OR LAWSON RESEARCH INSTITUTE OF ST. JOSEPH'S · Jan 30, 2025
Trial Information
Current as of July 09, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is investigating how certain brain activity patterns, measured by a simple and non-invasive test called electroencephalography (EEG), are linked to the development of postoperative delirium in patients with Parkinson's disease who are undergoing surgery. Postoperative delirium is a condition that can cause confusion and disorientation after surgery, and people with Parkinson's disease may be especially vulnerable to it. By identifying specific EEG patterns, like "burst suppression," which could indicate increased sensitivity to anesthesia, the researchers hope to improve anesthesia management and potentially reduce recovery time and hospital stays for these patients.
To be eligible for this study, participants must be adults aged 18 or older who have been diagnosed with Parkinson's disease and are scheduled for elective neurosurgery to implant a deep brain stimulator. They cannot have any pre-existing delirium or be undergoing emergency surgery. If you or a loved one meets these criteria, this trial could offer valuable insights and contribute to better care for individuals with Parkinson's disease during and after surgery. Participants will have their brain activity monitored throughout the procedure, helping doctors tailor anesthesia more effectively to improve patient outcomes.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Diagnosis of Parkinson's disease
- • 2. Elective neurosurgery for implantation of DBS electrodes and implantable pulse generator (IPG) device.
- • 3. 18 years of age or older
- Exclusion Criteria:
- • 1. Refusal/withdrawal of consent
- • 2. Inability to place sensor/ record EEG for the entire duration of surgery
- • 3. Emergency surgery
- • 4. Redo surgery
- • 5. Preoperative delirium (defined as per 3D CAM score)
About London Health Sciences Centre Research Institute Or Lawson Research Institute Of St. Joseph's
The London Health Sciences Centre Research Institute, affiliated with Lawson Health Research Institute at St. Joseph's Health Care, is dedicated to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into practical applications, the institute fosters collaboration among leading researchers, clinicians, and healthcare professionals. It aims to improve patient outcomes and enhance the quality of care through rigorous investigation in areas such as cancer, cardiovascular health, and neuroscience. By integrating cutting-edge research with clinical practice, the institute plays a pivotal role in shaping the future of healthcare delivery in the community and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Sujoy Banik, MD
Principal Investigator
Western University, London Health Sciences Centre
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported