Outcomes of Complete Versus Partial Preservation of the Sub-valvular Apparatus in Cases of Mitral Valve Replacement

Launched by ASSIUT UNIVERSITY · Feb 1, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at different ways to preserve parts of the heart during mitral valve replacement surgery. Specifically, it will compare two approaches: one where both important parts of the heart (called leaflets) are kept intact, and another where only one part is preserved. The goal is to see which method leads to better outcomes for patients with mitral valve problems, particularly those caused by rheumatic disease.

To be eligible for this trial, participants need to be between 18 and 60 years old and have specific heart conditions that require replacement of the mitral valve. However, individuals who have had previous heart surgeries or certain serious health issues are not eligible to participate. While the trial is not yet recruiting participants, those who join can expect to have their health monitored closely as researchers gather information on how effective each surgical method is. This study aims to help improve future treatments for patients undergoing mitral valve replacement.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Age between 18 and 60 years
• • Rheumatic mitral disease indicated for mitral valve replacement
• • Concomitant other valve disease
• Exclusion Criteria:
• • - Patients who have undergone previous mitral valve surgery or other heart surgery.
• • Patients with ischemic mitral disease.
• • emergency operation.
• • patients with significant comorbidities (severe pulmonary disease or end stage renal disease).