This Study Aims to Explore the Efficacy of Hyperbaric Oxygen in the Treatment of Flap Ischaemic Necrosis After Breast Cancer Surgery

Launched by GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL · Feb 1, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at whether hyperbaric oxygen therapy can help treat flap ischaemic necrosis, a condition that can occur after breast cancer surgery. This condition happens when the blood supply to a part of the skin used in surgery (called a flap) is reduced, leading to potential tissue damage. The researchers want to see if providing extra oxygen in a special pressurized chamber can improve healing in these cases.

To participate in this study, women aged 18 to 60 who have had breast cancer surgery and have a specific type of flap issue may be eligible. Participants will need to understand the study and agree to take part by signing a consent form. However, certain health conditions, such as severe lung diseases or eye problems, may prevent someone from joining the trial. The study is not yet recruiting participants, but if you or someone you know might be interested, it could be a way to explore new treatment options for healing after surgery.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. understand the study procedure, participate in the study voluntarily and sign the informed consent form
• • 2. aged ≥ 18 years and ≤ 60 years, female
• • 3. ECOG 0-2
• • 4. patients with The SKIN Score Degree of B-D and The SKIN area of 1-3 in the Clavien-Dindo classification after breast cancer surgery；
• Exclusion Criteria:
• • 1. Contraindications to hyperbaric oxygen therapy: lung disease (severe chronic obstructive airway disease, herpetic lung disease, acute or chronic lung infection, uncontrolled asthma, untreated pneumothorax), history of previous middle ear surgery, middle ear disease (Eustachian tube dysfunction, recurrent episodes of vertigo), eye disease (retinal detachment).
• • 2. Pregnancy or lactation.
• • 3. any other condition that the investigators think the patient is unsuitable for participation in the study