Muscle Endurance in Children With Cystic Fibrosis

Launched by BEZMIALEM VAKIF UNIVERSITY · Feb 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how well children with cystic fibrosis (CF) can use their muscles, especially the muscles involved in breathing and those in the core and legs. CF is a genetic condition that causes thick mucus to build up in the lungs and other organs, leading to breathing difficulties and other health issues. The researchers want to compare the muscle strength and endurance of children with CF to that of healthy children, helping to understand how CF affects physical fitness and overall quality of life.

To participate in this study, children aged 6 to 18 with a confirmed diagnosis of CF and good lung function (measured by a test called FEV1) are eligible. Healthy children in the same age range can also join. Participants will undergo simple tests to measure their muscle strength and endurance. It's important to note that those with certain health issues or recent respiratory infections won't be able to take part. This study aims to gather valuable information that could help improve care for children with CF in the future.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria for Children with Cystic Fibrosis
• • Being between the ages of 6-18,
• • Being diagnosed with Cystic Fibrosis according to the American Cystic Fibrosis Association consensus guideline,
• • Having a forced expiratory volume in one second (FEV1) above 40% of the predicted value
• • Exclusion Criteria for Children with Cystic Fibrosis
• • Not being able to cooperate with the assessment methods performed in the study
• • Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
• • Having a history of exacerbation in the last month
• • Having an organ transplantation history
• • Using systemic corticosteroids
• • Inclusion Criteria for Healthy Children
• • - Being between the ages of 6-18
• • Exclusion Criteria for Healthy Children
• • Not being able to cooperate with the assessment methods performed in the study
• • Having an orthopedic, neurological, vestibular, etc. problem that may negatively affect the assessment methods performed in the study
• • Having had a respiratory tract infection in the last month