Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy

Launched by CAIRO UNIVERSITY · Feb 4, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring whether adding magnesium sulfate to a local anesthetic can help manage pain more effectively for patients undergoing a modified radical mastectomy, which is a type of surgery for breast cancer. The goal is to see if this combination can improve pain control after the procedure, making recovery more comfortable for patients.

To participate in this study, you need to be a woman aged 18 or older who is scheduled for this specific surgery. You should also have a certain level of physical health, as determined by your doctor. However, some individuals cannot join, such as those with bleeding disorders, active drug abuse, or certain liver and kidney conditions. If you decide to participate, you'll receive the treatments being studied, and researchers will monitor your pain levels to see how well the approach works. This trial is currently recruiting participants, and your involvement could help improve pain management for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥18 years.
• • Female gender.
• • American Society of Anesthesiologists (ASA) physical status II or III.
• • Patients scheduled for elective modified radical mastectomy for breast cancer.
• • Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2.
• Exclusion Criteria:
• • Bleeding tendency due to coagulopathy,
• • Patients with opioid dependence or alcohol or drug abuse,
• • Significant liver and renal sufficiency
• • Patients with psychiatric illnesses that prevent them from proper perception and assessment of pain.
• • Local infection at the site of the block.
• • Known hypersensitivity or allergy to magnesium sulfate or local anesthetics.
• • Patients with chronic pain syndromes or pre-existing neuropathic pain conditions.
• • Pregnant or lactating individuals.