Validation of an Algorithm for the Diagnosis of Sarcopenic Obesity

Launched by ELISA GIANNETTA · Feb 4, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a condition called sarcopenic obesity (SO), which occurs when a person has both high body fat and low muscle mass. The researchers want to see if a specific set of guidelines, known as the ESPEN-EASO algorithm, can accurately identify SO by looking at blood markers and how well people can perform physical activities. They plan to enroll 150 participants, with 75 having sarcopenic obesity and 75 as a comparison group of people with regular obesity.

To participate, individuals need to be between the ages of 65 and 74, have a body mass index (BMI) of 30 or higher, and be of Caucasian descent. However, those with certain health conditions or who take specific medications that might affect body composition will not be eligible. Participants can expect to undergo various tests, complete questionnaires, and provide blood samples to help the researchers gather important information. This study aims to improve the understanding and diagnosis of sarcopenic obesity, which could have a positive impact on public health. The researchers are committed to protecting the privacy of all participants and ensuring ethical standards are met throughout the trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • BMI equal more than 30
• • Caucasians
• Exclusion Criteria:
• • any disease or medication that can significantly affect body composition (eg.malignant diseases in the last 5 years, autoimmune diseases, neurological diseases, syndromic obesity),
• • level of physical activity more than 3 METS
• • alcohol intake more than 140g/wk for M and 70g/wk for F
• • participation in a weight-reducing program (last 3 months),
• • impossibility to perform DXA exam
• • pregnancy and breast-feeding.