Remote vs. In-Person Study Evaluation (RISE) Trials: RISE Above Smoking (Trial 1)

Launched by STATE UNIVERSITY OF NEW YORK AT BUFFALO · Feb 6, 2025

Keywords

ClinConnect Summary

The RISE Above Smoking Trial is a research study designed to compare two ways of helping people quit smoking: through remote support using your phone or computer, and in-person visits at a clinic. If you decide to participate, you’ll first go through a quick screening to see if you’re eligible. If you qualify, you’ll be assigned to one of the two groups for treatment and follow-up over a three-month period. This trial aims to understand which method is more effective for helping smokers quit.

To be eligible for this study, you need to be over 18 years old, a daily smoker of more than five cigarettes, and motivated to quit. You’ll also need to have a smartphone and be comfortable reading and understanding English. It’s important to note that if you’re currently using other nicotine products (like vaping or chewing tobacco), or if you have certain health conditions, you may not be eligible. This study is not yet recruiting, but it will be a valuable opportunity for those looking to quit smoking with either remote or in-person support.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Common to all 3 RCTs:
• Inclusion criteria:
• • 1. age \>18 years
• • 2. stable mailing address (for mailing study packets if assigned to Remote Intake and/or Remote Treatment/Assessment) within accessible range of each study site
• • 3. able to read, speak \& verbally comprehend English
• • 4. own an iOS or Android smartphone
• • 5. have a valid e-mail address that is checked regularly or have regular access to text messages (to access follow-up assessments)
• Specific to RCT 1:
• Inclusion criteria:
• • 1. daily cigarette smoker of \>5 cigs/day
• • 2. moderate or greater motivation to quit smoking (6+ on the Motivation to Stop Smoking Scale63
• • 3. willingness to use dual NRT to quit
• • 4. agree to refrain from use of other tobacco products and use of non-study cessation treatments while participating in the trial
• Exclusion Criteria:
• * Specific to RCT 1:
• • 1. use of tobacco/nicotine products other than cigarettes more than once per week
• • 2. prior allergy/intolerance to NRT patch or lozenge
• • 3. FDA-specified contraindications for use of NRT
• • 4. use of tobacco/nicotine products other than cigarettes more than once per week
• • 5. prior allergy/intolerance to NRT patch or lozenge
• • 6. FDA-specified contraindications for use of NRT
• • 7. . pregnant, breastfeeding, or planning to become pregnant
• • 8. self-reported recent (past 1 month) cardiovascular event: MI, stroke
• • 9. current use of any smoking cessation medication or antipsychotic medication
• • 10. daily/near-daily binge drinking or alcohol dependence (NIDA Quick Screen; AUDIT\>15)
• • 11. high risk involvement with illicit or nonmedical prescription drugs (NIDA-modified ASSIST\>=27)
• • 12. past-year suicide attempt
• • 13. active and unstable major medical/psychiatric conditions