Hypertonic Saline in Posterior Spinal Fusion

Launched by JOSEPH D. TOBIAS · Feb 6, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating the effects of two different types of saline solutions used during brain surgery in young patients aged 8 to 21. One group of participants will receive a standard 0.9% normal saline solution, while the other group will receive a special buffered 2% hypertonic saline solution. The main goal is to see how these fluids affect the body's chemistry during surgery, specifically looking at changes in acid-base balance and electrolyte levels. Researchers also want to find out which fluid requires less volume for effective treatment during the operation.

To be eligible for this study, participants must be scheduled for a specific type of brain surgery that involves monitoring blood pressure through an arterial line and need to have two intravenous lines placed. If the surgery does not require these specific monitoring techniques, the patient will not be eligible. As the trial is not yet recruiting, interested families will need to wait for further announcements regarding participation. This study aims to improve care for young patients undergoing crucial neurological procedures.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients \> or = 10 years of age
• • ASA 1-3
• • Undergoing a PSF procedure requiring two peripheral intravenous infusions and an arterial cannula
• Exclusion Criteria:
• • Arterial cannula is not indicated for the surgical procedure
• • Two peripheral intravenous cannulas are not required
• • An invasive arterial cannula cannot be placed