Functional Cereal Products and Contribution to the Regulation of Metabolism and Obesity-induced Chronic Low-grade Inflammation.

Launched by HAROKOPIO UNIVERSITY · Feb 6, 2025

Keywords

ClinConnect Summary

The effect of consuming the new bread product, a white wheat bread enriched with oat beta-glucans, on metabolic and inflammatory markers after an 8-week dietary intervention in volunteers with overweight/obesity will be studied. The volunteers will be randomly divided into two groups: group 1 (control) which will receive the conventional product i.e., white wheat bread and group 2 (intervention) which will receive the beta-glucans enriched bread. Both products will be consumed in isocaloric amounts and volunteers in both groups will follow a hypocaloric diet.

The following procedures/deter...

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Eligibility criteria

• Inclusion Criteria:
• • no underlying diseases
• • with LDL-cholesterol levels between 115-150 mg/dL
• • with 25\<BMI\<32 kg/m2
• • with stable body weight in the last 3 months before the intervention
• • with normal diet and exercise habits
• Exclusion Criteria:
• • not suffer from diabetes mellitus, cardiovascular disease, chronic renal failure
• • not receive hypolipidemic treatment
• • not receive nutritional supplements that may affect blood lipid levels (eg omega-3 supplements, plant sterols/stanols) or the intestinal microbial flora (probiotics/prebiotics/antibiotics).
• • not be pregnant or lactating
• • not have food allergies
• • not have habits that prevent their compliance with the research protocol