Orthodontic Treatment on Oral Microbiota and Salivary Proteins

Launched by XI'AN JIAOTONG UNIVERSITY · Feb 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how orthodontic treatment, like braces, affects the bacteria in the mouth and the proteins found in saliva in children and teenagers aged 8 to 18. The research will take place at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027. Before starting treatment, participants will have some routine check-ups, sign consent forms, and complete questionnaires about their oral health and feelings about their dental care. Throughout the treatment, researchers will collect samples of plaque and saliva at regular intervals to see how the mouth’s bacteria change.

To be eligible for this trial, participants must not have any dental cavities or missing teeth, and they should not have a history of dental treatments or specific health conditions. They also need to be able to attend follow-up appointments regularly. This study aims to gather valuable information that can help improve oral health during orthodontic treatment, so if you or your child meet the criteria, it could be a great opportunity to contribute to important research while receiving orthodontic care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • No carries and White spot
• • No missing teeth
• • No history of oral treatment
• • No malocclusion
• • No systemic diseases
• Exclusion Criteria:
• • Antibiotic use in the past three months
• • A history of long-term medication use
• • A history of dental fillings
• • Unable to attend regular follow-ups