Asian-Mediterranean Diet and Women's Health

Launched by GLOBAL CENTRE FOR ASIAN WOMEN'S HEALTH · Feb 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a healthy diet inspired by the Mediterranean way of eating, tailored for Asian women, to see how it can improve their health, especially regarding heart and metabolic health. The researchers believe that by focusing on Asian women who are overweight or obese, particularly those between the ages of 21 and 50, they can develop effective strategies to promote better health not just for these women, but also for their families.

To participate in this study, women must be of Chinese ethnicity, live in Singapore, and have a body mass index (BMI) of 23 to 37.5, which indicates they are overweight. They should not be pregnant or breastfeeding, planning to conceive soon, or have certain health conditions that could affect the study's results. Participants will be asked to complete questionnaires and may also undergo tests to monitor their health. This trial is a great opportunity for women looking to improve their health through diet and contribute to important research that could benefit others in their community.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• Subjects must meet all of the inclusion criteria for participation:
• • 1. Females aged 21-50 years
• • 2. Chinese ethnicity
• • 3. Singapore citizens, permanent residents, or long-term pass holders
• • 4. Is able to complete questionnaires in English
• • 5. BMI ≥ 23.0 kg/m2 but \< 37.5 kg/m2
• • 6. Not planning to conceive in the next 12 months from enrolment (you will be asked to withdraw once you conceive during the study period)
• • 7. Not planning to leave Singapore for more than 2 consecutive calendar weeks (10 working days) in the next six months from enrolment
• • 8. Not currently pregnant or breastfeeding
• • 9. Not currently smoking
• • 10. Without history of major chronic diseases (e.g., cancer, diabetes, cardiovascular diseases, chronic kidney disease), major infectious diseases (e.g. hepatitis B, HIV), severe gastrointestinal disorders (e.g. colitis or inflammation of the bowel, celiac disease, chronic gastritis) and major medical procedures/surgeries related to these conditions
• • 11. Without major mental health condition
• • 12. Without known food allergies, especially to nuts and seafood.
• • 13. Not on any special diets or having dietary restrictions (e.g. vegetarians, vegans, ketogenic, Kosher diet)
• • 14. Not currently and will not be enrolled in another interventional study or studies that may affect weight, cardiometabolic health, gut, or brain health in the next six months from enrolment
• Exclusion Criteria:
• • Subjects not meeting any of the above inclusion criteria will be excluded from participation.
• Additional Exclusion Criteria for MRI procedure only:
• • i. Shoulder width ≥60cm ii. Has any medical implants or foreign bodies, particularly related to heart, brain, or eye implants, including but not limited to pacemakers, artificial heart valves, implantable cardioverter defibrillators, ventricular assist devices, brain stimulation devices, intrauterine devices, and breast biopsies (if any implant or tissue marker has been placed) iii. History of head injury or trauma with loss of consciousness iv. Metallic dental braces or dental implants v. Having claustrophobia vi. Drinks more than 30 units of alcohol per week (1 unit = 25mL 40% spirit, 1 can of beer = 2 units, 1 standard glass of wine = 2 units)