Sodium Bicarbonate Intake on Endurance Performance

Launched by HACETTEPE UNIVERSITY · Feb 10, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how sodium bicarbonate (commonly known as baking soda) might help improve running performance for female runners. Specifically, it will test whether taking sodium bicarbonate with a meal rich in carbohydrates can enhance endurance during high-intensity running. The researchers want to see if this method can improve how long and how well recreational female runners can perform over a 10 km distance, while also monitoring any stomach discomfort and changes in blood chemistry during exercise.

To participate in this study, women aged 18 to 40 who are regular runners (training at least three times a week and have experience in 10 km races) may be eligible. Participants should be able to run 10 km at a pace of less than 6 minutes per kilometer. During the trial, each participant will take either sodium bicarbonate or a placebo (a harmless substance), followed by a time-trial run. The study involves two testing sessions scheduled at specific times in relation to their menstrual cycle, and participants will be monitored for their running performance, heart rate, and any side effects they might experience.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female, aged 18-40.
• • Recreational runner with a minimum one-year history of regular training (at least three days per week).
• • Experience in races of 10 km or more (verified by an official race result).
• • Ability to complete a 10 km distance at an average pace below 6.00 min/km (confirmed through best-record evidence via applications like Strava).
• Exclusion Criteria:
• • Usage of any medications or supplements that could impact metabolism.
• • Presence of any acute or chronic condition limiting physical activity (musculoskeletal, cardiovascular, or respiratory issues).
• • Alcohol and/or smoking habits.
• • Adherence to a specific diet influencing metabolism during the study period (intermittent fasting, ketogenic, vegan diets, etc.).
• • Pregnancy or breastfeeding during the study period.
• • Severe menstrual irregularities or amenorrhea.
• • Body Mass Index (BMI) outside the range of 18.5-30.
• • History of gastrointestinal disorders (e.g., IBS, Crohn's disease).
• • Allergy or intolerance to sodium bicarbonate or related compounds.
• • History of disordered eating.