Cervical TsDCS on Stroke Patients

Launched by IRCCS SAN RAFFAELE ROMA · Feb 12, 2025

Keywords

ClinConnect Summary

This clinical trial, called "Cervical TsDCS on Stroke Patients," is investigating a new way to help stroke patients recover better use of their arms and hands. The study will examine whether a treatment called transcranial direct current stimulation (tsDCS) can improve strength and coordination in patients who have experienced a stroke. The goal is to see if this type of brain stimulation can make daily activities easier for those affected by weakness in their upper limbs after a stroke.

To participate in the trial, you need to be at least 18 years old and have had your first stroke (either from a blockage or bleeding) within the last 30 days. You should also have mild to moderate symptoms and some remaining use of your arms. However, if you have severe muscle stiffness, trouble speaking, or other significant health issues, you may not be eligible. Participants can expect to receive the tsDCS treatment and will be monitored for its effects on their motor skills. This study is not yet recruiting participants, but it aims to explore new ways to assist stroke recovery, which could be beneficial for many people facing these challenges.

Gender

ALL

Eligibility criteria

• Group Stroke:
• Inclusion criteria:
• • 1. age over 18 years;
• • 2. first ischemic/hemorrhagic stroke (within 30 days of onset);
• • 3. mild-to-moderate stroke (NIHSS scale score\<16).
• • 4. residual function of the upper limb, assessed by the following scales: - MRC of the distal muscles of the upper limb: score between 2 and 4; - NHISS (items 5A and 5B): score between 1 and 3;
• • 5. ability to give informed consent and understand instructions.
• Exclusion criteria:
• • 1. severe spasticity (Ashworth Scale score \> 2);
• • 2. severe aphasia;
• • 3. severe neglect;
• • 4. history of disabling neurological disease;
• • 5. history of epilepsy;
• • 6. significant comorbidities;
• • 7. contraindications to tsDCS.
• Healthy Group:
• Inclusion criteria:
• • 1. age over 18 years;
• • 2. equalized in age with the patient group.
• Exclusion criteria:
• • 1. history of stroke progress;
• • 2. history of severe neurological disease.