Social Cognition Training in Individuals With Huntington's Disease

Launched by RUSH UNIVERSITY MEDICAL CENTER · Feb 11, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to help people with Huntington's Disease improve their social skills through something called computerized social cognition training. Social cognition is about understanding how other people feel and think, which is important for interacting with them effectively. People with Huntington's Disease often struggle with these skills, which can affect their relationships and overall well-being. The researchers believe that this training can not only help those with Huntington's Disease but also make life easier for their caregivers, who often face significant challenges.

To participate in the trial, individuals with Huntington's Disease must be between 18 and 65 years old, diagnosed through genetic testing, and able to understand and read English. They should also be stable on their medications and have access to a computer or mobile device. Caregivers living with these individuals can also join if they meet similar age and language requirements. Participants will attend in-person visits over a few months to take part in the training and assessments. This study is a first step to see if the training is feasible and beneficial before moving on to a larger trial.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria for Individual with Huntington's Disease
• • Diagnosed with Huntington's Disease based on genetic testing
• • Must be between 18 and 65 years of age
• • Native English speaker who is literate in English
• • Stable psychotropic medication regimen for 4 weeks
• • Must have a score of "somewhat easily" on all items in the CPQ-12
• • MOCA \>18
• • Completed 12 years of schooling
• • Access to laptop or mobile device
• • Willingness to come in person 6-12 weeks after first visit
• • Inclusion Criteria for Caregiver of Individual with Huntington's Disease
• • Lives with patient
• • Must be between 18 and 65 years of age
• • Native English speaker who is literate in English
• • MOCA \>26
• • Willingness to come in person within 6-12 weeks after first visit
• • Exclusion Criteria for Individual with Huntington's Disease
• • Any known neurological condition (other than Huntington's Disease).
• • History of learning and/or intellectual disabilities
• • Currently actively involved in any other interventional trial (i.e. have begun the intervention) or within 4 weeks of completing the final assessments of an interventional trial.
• • Currently regularly completing a computerized cognitive training intervention.
• • Active suicidal ideation with some intent
• • Exclusion Criteria for Caregiver of Individual with Huntington's Disease
• • Inability to provide informed consent
• • Active suicidal ideation with some intent