Clinical and Radiographic Success Following Regenerative Pulpotomy Using Chitosan Hydrogel Versus Platelet Rich Fibrin in Mature Mandibular Molars

Launched by CAIRO UNIVERSITY · Feb 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different treatment methods for patients with painful mature molars that have a condition called symptomatic pulpitis, which means the pulp (the innermost part of the tooth) is inflamed. The goal is to determine how well these treatments—using chitosan hydrogel or platelet rich fibrin—work in relieving pain and ensuring the tooth remains healthy over time.

To participate in this study, potential candidates need to be adults with mature molars that respond positively to a cold test (indicating that the tooth is still alive), and they should be free from severe gum disease or other serious health issues that could affect healing. Participants will also need to agree to join follow-up appointments over six months. Those with certain conditions, like infections or very young or old age, won't be eligible. Throughout the trial, participants can expect to receive one of the treatments and will be monitored for their recovery and any pain they experience afterward.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients suffering from Symptomatic pulpitis in mature mandibular molars only will be involved.
• • Tooth should give positive response to cold test
• • Haemostasis should be achieved after full pulpotomy
• • The tooth is restorable and free from advanced periodontal disease, cracks and splits.
• • Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
• • Patients who will agree to the consent and will commit to follow-up period.
• • Patients with mature root apices
• • Patients with no internal or external resorption and no periapical lesions
• • Soft tissues around the tooth are normal with no swelling or sinus tract
• Exclusion Criteria:
• • Patients with immature roots.
• • Haemostasias after 10 minutes cannot be controlled after full pulpotomy Patients with any systemic disease that may affect normal healing.
• • Patients with periapical lesions or infections.
• • Pregnant females.
• • Patients who could/would not participate in a 6 months follow-up.
• • Patients with fistula or swelling
• • Patients with necrotic pulp.
• • Patients with old age.