The Efficacy of Modified Olfactory Training Method for Patients With Post-viral Olfactory Dysfunction

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Feb 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new device designed to help people who have lost their sense of smell after a viral infection, a condition known as post-viral olfactory dysfunction. The main goal is to see if this modified device works better than a standard olfactory training device in helping patients regain their sense of smell. The trial is currently looking for participants aged 18 to 80 who have been diagnosed with this condition and can complete the required tests.

To take part in the study, participants must not have certain other conditions that could affect their sense of smell, such as chronic diseases or recent treatments that impact olfactory recovery. Those who join the trial can expect to undergo tests to measure their sense of smell and use the modified device as part of their treatment. It's important to note that this study is voluntary, and participants will need to sign a consent form to take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18-80 years old, gender not limited.
• • 2. Patients diagnosed with olfactory dysfunction following infections of the upper respiratory tract, as determined by Sniffin' Sticks test (including TDI value test).
• • 3. Voluntarily signs the informed consent form.
• Exclusion Criteria:
• • 1. Patients with post-traumatic olfactory dysfunction, rhinosinusitis-related dysfunction and olfactory dysfunction caused by other reasons.
• • 2. Patients with concomitant sinonasal disease.
• • 3. Patients with chronic diseases, such as hypertension, diabetes, bronchopneumonia, chronic obstructive pulmonary disease, etc.
• • 4. Patients with serious coexisting diseases: such as malignant tumors, etc., with a life expectancy of less than 2 years.
• • 5. Patients who cannot tolerate olfactory function testing and treatment.
• • 6. Patients who have taken oral glucocorticoids, antibacterial drugs, anti-leukotrienes, antihistamines, or received olfactory training within four weeks will be excluded.
• • 7. Patients who are receiving treatment that affects olfactory recovery.
• • 8. Patients with smoking habits.
• • 9. Patients who are already or plan to be pregnant.
• • 10. According to the judgment of the researchers, the patient cannot complete this study or cannot comply with the requirements of this study (such as memory or behavior abnormalities, depression, heavy drinking, previous breach of contract).
• • 11. Patients who did not consent for participating in the study.