The Effect of Uterine Entry In Fetoscopic Laser Photocoagulation for Twin-To-Twin Transfusion Syndrome

Launched by BAYLOR COLLEGE OF MEDICINE · Feb 11, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring how the method used by surgeons to enter the uterus during a specific procedure called fetoscopic laser photocoagulation affects the separation of membranes surrounding the babies in cases of twin-to-twin transfusion syndrome. This condition occurs in identical twins who share a placenta, where one twin may receive more blood than the other, leading to health complications. The trial aims to find out if different entry techniques can influence the outcomes for these pregnancies.

To participate in this study, women who are pregnant with complicated identical twins (monochorionic-diamniotic twins) and have been advised to undergo this laser treatment may be eligible. However, those expecting triplets or more, or who choose not to have the treatment, cannot join. If you decide to participate, you will help researchers understand how the surgical approach might impact the health of both babies. The trial is currently looking for participants, so it's a good time to ask your doctor for more information if you're interested.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Patients who are eligible and elect to undergo fetoscopic selective laser photocoagulation for complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
• Exclusion Criteria:
• • Patients who do not elect to undergo fetoscopic laser photocoagulation for the treatment of complicated monochorionic-diamniotic twin pregnancies with twin-to-twin transfusion syndrome.
• • Triplets and higher order multiple gestations.