Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients

Launched by İBRAHIM EMIR YEŞIL · Feb 11, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how certain imaging tests, bone health, and hearing ability are connected in adults with a condition called otosclerosis, which affects hearing. The researchers want to find out if there is a relationship between the results of a special type of X-ray called a temporal bone CT scan and the level of hearing loss these patients experience. They will also compare the bone mineral density (which is a measure of bone strength) and vitamin D levels between people with otosclerosis and those without it, to see if these factors differ.

To participate in the study, individuals need to be adults diagnosed with otosclerosis and have had a temporal bone CT scan, along with other audiological tests. They are also looking for a control group of adults without otosclerosis who have had similar imaging done for different reasons. Participants will have their bone density measured, vitamin D levels checked, and undergo hearing tests. The goal of this research is to better understand otosclerosis by gathering information from imaging, bone health, and hearing tests, which could help with future diagnoses and treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria (Otosclerosis Group):
• • Adults diagnosed with otosclerosis based on audiological and clinical assessment
• • Patients with available high-resolution CT scans and audiological data
• • Individuals who have undergone stapedectomy or stapedotomy surgery
• • Availability of bone mineral density and serum vitamin D data
• Inclusion Criteria (Control Group):
• • Patients without otosclerosis but with temporal CT imaging for other indications
• • No history of conductive or mixed hearing loss
• • Availability of BMD and vitamin D data
• Exclusion Criteria:
• • History of primary metabolic bone diseases (osteoporosis, Paget's disease)
• • Use of medications affecting bone metabolism (bisphosphonates, corticosteroids)
• • History of chronic otitis media or prior ear surgeries
• • Patients who received head and neck radiotherapy