Acute Concussion Management in Emergency Medicine with 7T MRI: a Feasibility Study

Launched by NHS GREATER GLASGOW AND CLYDE · Feb 11, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Acute Concussion Management in Emergency Medicine with 7T MRI: a Feasibility Study," is focused on understanding how a special type of brain scan called a 7T MRI can show changes in the brain after a concussion. Researchers want to see if there are differences in the brain images of patients who fully recover from a concussion compared to those who continue to have symptoms about 28 days after their injury. The study will include adults aged 18 to 40 who come to the Emergency Department within 96 hours of a head injury and have had a normal CT scan of their brain.

If you or someone you know has had a head injury and meets these criteria, you might be eligible to participate. During the study, participants will undergo a 7T MRI scan to help researchers learn more about how concussions affect the brain. This research could be important for improving how we understand and treat concussions in the future. It's important to note that the trial is not yet recruiting participants, but it aims to provide valuable insights into concussion management.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Isolated head trauma
• • 2. Initial review within 96h of injury
• • 3. No acute findings on CT head
• • 4. Aged 18-40 years
• Exclusion Criteria:
• • 1. Patient unable to give informed consent
• • 2. Patient unable to speak and understand English
• • 3. Patients where alternative diagnosis cannot be excluded
• • 4. Polytrauma
• • 5. Contra-indication to MRI
• • 6. BMI \>40 or unable to comfortably lie on MRI scanner
• • 7. Pregnant
• • 8. Major confounding neurological disease e.g Multiple sclerosis, Stroke, Parkinson's Disease.
• • 9. Patient participation in other research studies concurrently